
Off-Label
Off Label is an AI-hosted podcast by Dr. Steve Rondeau’s digital twin. It explores the limits of DSM-based diagnosis and the promise of brain-informed psychiatry. From mislabeled symptoms to overlooked patterns, we examine how mental health can evolve beyond outdated frameworks toward something more precise, personal, and real.
Off-Label
The Self-Criticism Circuit: How Your Brain Fuels Negative Self-Talk
Why are some people constantly hard on themselves, no matter how much they achieve? In this episode, we explore the neuroscience behind perfectionism and negative self-talk—specifically, how a pattern called Posterior Alpha Asymmetry (PAA) shows up on EEG scans of highly self-critical individuals. We break down what this brain pattern means, how it distorts perception, and why it’s more than just a mindset issue. If you’ve ever struggled with your inner critic, this episode will change how you see yourself—and your brain.